» » Handbook of Pre-Clinical Continuous Intravenous Infusion

Handbook of Pre-Clinical Continuous Intravenous Infusion epub download

by Guy Healing,David Smith


Read instantly in your browser. This is a useful text if you are running infusion studies. It had the facts that I was seeking. I got a used copy for little money.

Read instantly in your browser. ISBN-13: 978-0748408672.

Handbook of Pre-Clinical Continuous Intravenous Infusion. Six animals were treated with intravenous infusion of new synthetic antiprotease. Nafamostat Mesilate, at a dose of 1 mg/kg/h

Cite this publication. Handbook of Pre-Clinical Continuous Intravenous Infusion. Nafamostat Mesilate, at a dose of 1 mg/kg/h. Four out of seven untreated animals died during the experiment.

Start by marking Handbook of Pre-Clinical Continuous Intravenous Infusion as Want to Read .

Start by marking Handbook of Pre-Clinical Continuous Intravenous Infusion as Want to Read: Want to Read savin. ant to Read.

oceedings{P, title {Handbook of pre-clinical continuous intravenous infusion}, author {Guy . by Infusion Studies in the Rat P. Barrow CONTINUOUS INTRAVENOUS INFUSION IN THE MOUSE Femora. ONTINUE READING.

oceedings{P, title {Handbook of pre-clinical continuous intravenous infusion}, author {Guy Healing and David Nathan Smith}, year {2014} }. Guy Healing, David Nathan Smith. Guy Healing, David Smith. Introduction; D. Smith and G. Healing CONTINUOUS INTRAVENOUS INFUSION IN THE RAT Femoral Cannulation Using the Jacket/Harness Model in the Rat; O. Green and D. Patten Femoral Cannulation Using the Tail Cuff Exteriorisation Method in the Rat; A. McCarthy Tethering and the Implanted Button Model in the Rat; E. Miedel Multidose Infusion Toxicity Studies in the Rat G. Healing Reproductive Toxicology Studies.

Introduction; D. Healing. Continuous intravenous infusion in the rabbit. Continuous intravenous infusion in the rat. Femoral Cannulation Using the Jacket/Harness Model in the Rat; O. Patten. Femoral Cannulation Using the Tail Cuff Exteriorisation Method in the Rat; A. McCarthy. Tethering and the Implanted Button Model in the Rat; E. Miedel. Femoral Cannulation of the Rabbit for Reproductive Toxicity Studies C. Copeman and K. Robinson. Jugular Cannulation of the Rabbit for Reproductive Toxicity Studies E. Gordon and S. Lynch. Continuous intravenous infusion in the dog. Any scientist or technician involved in pre-clinical drug studies knows that infusing animal models with test substances is no simple matter, especially if one wants to do it humanely as well as guarantee results that are not compromised by the procedure. The challenge becomes compounded if one is employing a variety of species. What works for a rat or mouse does not necessarily work for a rabbit or primate.

Morton, Guy Healing, David Smith. What works for a rat or mouse does not necessarily work for a rabbit or primate

Intravenous infusion is a necessary mode of delivery for many pharmaceuticals currently on the market or. .

The technique of prolonged intravenous delivery in conscious, free-moving animal models has broadened the opportunity to study and evaluate the safety and efficacy of these therapeutic products. Following in the footsteps of the highly praised Handbook of Pre-Clinical Continuous Intravenous Infusion, this new volume covers both up-to-date procedures and equipment. It is organized by species, including all those commonly used in pre-clinical studies: rat, mouse, dog, minipig, large primate, and marmoset.

Intravenous infusion is a necessary mode of delivery for many pharmaceuticals currently on the market or.

Any scientist or technician involved in pre-clinical drug studies knows that infusing animal models with test substances is no simple matter, especially if one wants to do it humanely as well as guarantee results that are not compromised by the procedure. The challenge becomes compounded if one is employing a variety of species. What works for a rat or mouse does not necessarily work for a rabbit or primate. The Handbook of Pre-clinical Continuous Intravenous Infusion answers the needs of researchers and technicians by providing complete instructions for a wide range of infusion techniques delivered to several species. With sections devoted to rats, mice, rabbits, dogs, mini-pigs, and nonhuman primates (both large and small), this thorough text gives step-by-step instructions for the use of a variety of techniques, and equipment. It includes procedures for multidose infusion toxicity and reproductive toxicology studies, and provides guidance on the use of a variety of equipment, including tail cuffs, harnesses, and implanted buttons. It also offers detailed information on surgical preparation for primates and mini-pigs, along with advice about the use of preoperative anesthesia, post surgical analgesics, and antibiotic administration, as well as valuable input on surgical suite design. "… I was amazed and gratified about the level of detail and the practical emphasis on technical expertise and animal well-being. This book is unique in having that as an overt aim." From the Foreword, David B. Morton, University of Birmingham, UKThe text concludes with a chapter on general non-species-specific information that discusses common pathological findings in continuous infusion studies, the use of mini-osmatic pumps, and controllable variables such as vehicles, rates of administration and volumes. With contributions from several established experts in the handling of pre-clinical animal models, this authoritative volume removes the need for any guesswork, allowing technicians and researchers to proceed with confidence in undertaking critical studies.

Handbook of Pre-Clinical Continuous Intravenous Infusion epub download

ISBN13: 978-0748408672

ISBN: 0748408673

Author: Guy Healing,David Smith

Category: Medical Books

Subcategory: Medicine

Language: English

Publisher: CRC Press; 1 edition (August 31, 2000)

Pages: 344 pages

ePUB size: 1505 kb

FB2 size: 1638 kb

Rating: 4.5

Votes: 683

Other Formats: mobi lit lrf txt

Related to Handbook of Pre-Clinical Continuous Intravenous Infusion ePub books